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Select Safety Information for COREG
Do not abruptly stop taking COREG, as it may lead to acute exacerbation of coronary artery disease upon cessation of therapy. Bradycardia, hypotension, worsening heart failure/fluid retention may occur. Discuss these symptoms with your doctor. Tell your doctor about all the medications you take. Certain other medications may affect how COREG works.
IMPORTANT SAFETY INFORMATION AND INDICATIONS
Bradycardia, hypotension, worsening heart failure/fluid retention may occur. Discuss these symptoms with your doctor.
Tell your doctor about all the medications you take. Certain other medications may affect how COREG works.
Do not take COREG if you have any of the following:
- Bronchial asthma or related bronchospastic conditions
- Second- or third-degree AV block.
- Sick sinus syndrome.
- Severe bradycardia (unless permanent pacemaker in place).
- Patients in cardiogenic shock or decompensated heart failure requiring the use of IV inotropic therapy
- Severe hepatic (liver) impairment.
- History of serious hypersensitivity reaction (e.g., Stevens-Johnson syndrome, anaphylactic reaction, angioedema) to carvedilol or any of the components of COREG.
The most commonly reported side effects were:
- chest pain, discomfort, tightness, or heaviness
- dizziness, lightheadedness, or fainting
- generalized swelling or swelling of the feet, ankles, or lower legs
- shortness of breath
- slow heartbeat
- weight gain
You are encouraged to report negative side effects of prescription drugs to the FDA.
These highlights do not include all the information needed to use COREG safely and effectively. See full prescribing information for COREG.
Please read the accompanying Medication Guide for COREG, including the information about birth defects if taken during pregnancy, and discuss it with your doctor. The physician Prescribing Information also is available.